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Increased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein induction
Serine palmitoyltransferase, the first enzyme in ceramide biosynthesis, is required for resistance to heat shock. We show that increased heat shock sensitivity in the absence of serine palmitoyltransferase activity correlates with a lack of induction of the major heat shock proteins (Hsps) at high t...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC169048/ https://ncbi.nlm.nih.gov/pubmed/12881413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg375 |
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