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The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay

The C to U editing of apolipoprotein B (apoB) mRNA is mediated by a minimal complex composed of an RNA-binding cytidine deaminase (APOBEC1) and a complementing specificity factor (ACF). This editing generates a premature termination codon and a truncated open reading frame. We demonstrate that the A...

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Detalhes bibliográficos
Main Authors: Chester, Ann, Somasekaram, Angelika, Tzimina, Maria, Jarmuz, Adam, Gisbourne, Jane, O’Keefe, Raymond, Scott, James, Navaratnam, Naveenan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC169042/
https://ncbi.nlm.nih.gov/pubmed/12881431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg369
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