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SIFT: predicting amino acid changes that affect protein function

Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify amino acid substitutions in protein-coding regions. Each substitution has the potential to affect protein function. SIFT (Sorting Intolerant From Tolerant) is a program that predicts whether an amino acid substitut...

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Bibliografiske detaljer
Main Authors: Ng, Pauline C., Henikoff, Steven
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC168916/
https://ncbi.nlm.nih.gov/pubmed/12824425
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