טוען...
Redesign of substrate-selectivity determining modules of glutathione transferase A1–1 installs high catalytic efficiency with toxic alkenal products of lipid peroxidation
The evolution of proteins for novel functions involves point mutations and recombinations of domains or structural segments. Mimicking this process by rational design in vitro is still a major challenge. The present report demonstrates that the active site of the enzyme glutathione transferase (GST)...
שמור ב:
| Main Authors: | , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The National Academy of Sciences
2000
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC16877/ https://ncbi.nlm.nih.gov/pubmed/10900265 |
| תגים: |
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