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Residue 234 in glutathione transferase T1-1 plays a pivotal role in the catalytic activity and the selectivity against alternative substrates

GST (glutathione transferase) T1-1 plays an important role in the biotransformation of halogenated alkanes, which are used in large quantities as solvents and occur as environmental pollutants. Many reactions that are catalysed by GST T1-1 qualify as detoxification processes, but some reactions with...

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Detalhes bibliográficos
Main Authors: Shokeer, Abeer, Larsson, Anna-Karin, Mannervik, Bengt
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186729/
https://ncbi.nlm.nih.gov/pubmed/15683365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20042064
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