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Residue 234 in glutathione transferase T1-1 plays a pivotal role in the catalytic activity and the selectivity against alternative substrates

GST (glutathione transferase) T1-1 plays an important role in the biotransformation of halogenated alkanes, which are used in large quantities as solvents and occur as environmental pollutants. Many reactions that are catalysed by GST T1-1 qualify as detoxification processes, but some reactions with...

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Bibliografiska uppgifter
Huvudupphovsmän: Shokeer, Abeer, Larsson, Anna-Karin, Mannervik, Bengt
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press Ltd. 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186729/
https://ncbi.nlm.nih.gov/pubmed/15683365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20042064
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