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Presymptomatic detection or exclusion of prion protein gene defects in families with inherited prion diseases.

The identification of defects in the prion protein (PrP) gene in families with inherited Creutzfeldt-Jakob disease or Gerstmann-Straussler syndrome allows presymptomatic diagnosis or exclusion of these disorders in subjects at risk. After counseling, PrP gene analysis was performed in three such ind...

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Bibliografische gegevens
Hoofdauteurs: Collinge, J, Poulter, M, Davis, M B, Baraitser, M, Owen, F, Crow, T J, Harding, A E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1991
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1686464/
https://ncbi.nlm.nih.gov/pubmed/1684089
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