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Thermolabile enzymes in progeria and Werner syndrome: evidence contrary to the protein error hypothesis.

To test the hypothesis that widespread errors in protein synthesis underlie diseases with features resembling premature aging, we examined the thermostability of two erythrocyte enzymes in three unrelated progeria families and in two Werner syndrome patients. Unlike previous reports, no increased he...

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Main Authors: Brown, W T, Darlington, G J
格式: Artigo
語言:Inglês
出版: 1980
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1686133/
https://ncbi.nlm.nih.gov/pubmed/6930821
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