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Residual mannosidase activity in human mannosidosis: characterization of the mutant enzyme.

The prenatal diagnosis of affected fetuses in two families at risk for mannosidosis gave us the opportunity to study the residual alpha-mannosidase activity. We found an altered acidic alpha-mannosidase characterized by lowered affinity toward the substrate, displacement of maximal activity toward p...

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Bibliographische Detailangaben
Hauptverfasser: Poenaru, L, Miranda, C, Dreyfus, J C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1980
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1686056/
https://ncbi.nlm.nih.gov/pubmed/7386463
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