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Evidence for a hybrid hexosaminidase isoenzyme in heterozygotes for Sandhoff disease.

Patients with Sandhoff disease have less than 5% of normal levels of serum or tissue hexosaminidase activity. They are thought to have a defect in the structural gene for the beta chain of hexosaminidase (HEX). Heterozygotes for Sandhoff disease have approximately 50% of the total serum HEX activity...

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Библиографические подробности
Главный автор: Lowden, J A
Формат: Artigo
Язык:Inglês
Опубликовано: 1979
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1685792/
https://ncbi.nlm.nih.gov/pubmed/463876
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