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Detection of DNA damage by use of Escherichia coli carrying recA'::lux, uvrA'::lux, or alkA'::lux reporter plasmids.

Plasmids were constructed in which DNA damage-inducible promoters recA, uvrA, and alkA from Escherichia coli were fused to the Vibrio fischeri luxCDABE operon. Introduction of these plasmids into E. coli allowed the detection of a dose-dependent response to DNA-damaging agents, such as mitomycin and...

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Библиографические подробности
Главные авторы: Vollmer, A C, Belkin, S, Smulski, D R, Van Dyk, T K, LaRossa, R A
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC168554/
https://ncbi.nlm.nih.gov/pubmed/9212407
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