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Use of restriction fragment length polymorphisms for genetic counseling: Population genetic considerations

Two-locus population genetic models are analyzed to evaluate the utility of restriction fragment length polymorphisms for purposes of genetic counseling. It is shown that the linkage disequilibrium between a neutral marker and a tightly linked overdominant mutant will increase rapidly as the mutant...

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Detalhes bibliográficos
Main Authors: Asmussen, Marjorie A., Clegg, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1685346/
https://ncbi.nlm.nih.gov/pubmed/6282118
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