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Population heterogeneity of the Hpa I restriction site associated with the beta globin gene: implications for prenatal diagnosis.

The Hpa I restriction endonuclease site polymorphism that results in some human beta globin genes being contained in a 13-kilobase (kb) DNA restriction fragment rather than in the usual 7.6-kb fragment has been reported to be in linkage disequilibrium with the beta S mutation. The frequency of the 1...

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Detalhes bibliográficos
Main Authors: Panny, S R, Scott, A F, Smith, K D, Phillips, J A, Kazazian, H H, Talbot, C C, Boehm, C D
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1684869/
https://ncbi.nlm.nih.gov/pubmed/6162380
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