Evaluation of a novel subtilisin inhibitor gene and mutant derivatives for the expression and secretion of mouse tumor necrosis factor alpha by Streptomyces lividans.

In order to evaluate the expression and secretion signals of the highly secreted subtilisin inhibitor of Streptomyces venezuelae CBS762.70 (VSI) for the production of heterologous proteins by Streptomyces lividans, mouse tumor necrosis factor alpha (mTNF) was chosen as a model protein. The mTNF cDNA...

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Lammertyn, E, Van Mellaert, L, Schacht, S, Dillen, C, Sablon, E, Van Broekhoven, A, Anné, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC168474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9143114/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.63.5.1808-1813.1997
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