Enhanced protein secretion in reduced genome strains of Streptomyces lividans

Abstract Background S. lividans TK24 is a popular host for the production of small molecules and the secretion of heterologous protein. Within its large genome, twenty-nine non-essential clusters direct the biosynthesis of secondary metabolites. We had previously constructed ten chassis strains, car...

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Bibliografske podrobnosti

Principais autores:	Mohamed Belal Hamed, Tobias Busche, Kenneth Simoens, Sebastien Carpentier, Jan Kormanec, Lieve Van Mellaert, Jozef Anné, Joern Kalinowski, Kristel Bernaerts, Spyridoula Karamanou, Anastassios Economou
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2024-01-01
Serija:	Microbial Cell Factories
Teme:	Reduced genome strains Secretome Proteomics Transcriptomics Heterologous secretion
Online dostop:	https://doi.org/10.1186/s12934-023-02269-x
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