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Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting.

It is well recognized that age at onset of Huntington disease (HD) is strongly influenced by the sex of the affected parent, and this has lead to suggestions that genetic imprinting or maternal specific factors may play a role in the expression of the disease. This study evaluated maternal and pater...

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Autors principals: Farrer, L A, Cupples, L A, Kiely, D K, Conneally, P M, Myers, R H
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1684271/
https://ncbi.nlm.nih.gov/pubmed/1531729
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