Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor alpha: a role for kupffer cells?

BACKGROUND: It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release mitogenic factors leading to hepatic hyperplasia, and eventually cancer. However, Kupffer cells do not express PPARα receptors, and PPARα agonists stimulate hepatocellular proliferation in...

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Hlavní autoři: Alsarra, Ibrahim A, Brockmann, William G, Cunningham, Michael L, Badr, Mostafa Z
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
Short Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1684246/
https://ncbi.nlm.nih.gov/pubmed/17129391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-5-26
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