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Frequent deletion and duplication of the steroid 21-hydroxylase genes.

Congenital adrenal hyperplasia due to 21-hydroxylase (21-OHase) deficiency is an HLA-linked disorder resulting from a mutation in the 21-OHase B gene encoding the adrenal cytochrome P450 specific for steroid 21-hydroxylation. To identify polymorphisms associated with 21-OHase deficiency, DNA samples...

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Autors principals: Werkmeister, J W, New, M I, Dupont, B, White, P C
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683994/
https://ncbi.nlm.nih.gov/pubmed/3490178
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