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Selective inhibition of HIV replication in primary macrophages but not T lymphocytes by macrophage-derived chemokine

Macrophage-derived chemokine (MDC) has been reported to inhibit different HIV-1 strains in activated peripheral blood mononuclear cells (T cell blasts), although other investigators have not confirmed these findings. Here we demonstrate that MDC inhibits the replication of CCR5-dependent (R5) HIV-1(...

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Bibliographic Details
Main Authors: Cota, Manuela, Mengozzi, Manuela, Vicenzi, Elisa, Panina-Bordignon, Paola, Sinigaglia, Francesco, Transidico, Pietro, Sozzani, Silvano, Mantovani, Alberto, Poli, Guido
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC16839/
https://ncbi.nlm.nih.gov/pubmed/10908681
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