Slot blot method for the quantification of DNA sequences and mapping of chromosome rearrangements: Application to chromosome 21

As an alternative to the methods of gene dosage based on either RFLP studies or Southern blots using specific and reference probes, we designed a “slot blot” method for the evaluation of the copy number of unique chromosome 21 sequences. Varying amounts of denatured DNA from a normal control, a tris...

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Bibliografiske detaljer
Main Authors: Blouin, J. L., Rahmani, Z., Chettouh, Z., Prieur, M., Fermanian, J., Poissonnier, M., Leonard, C., Nicole, A., Mattei, J. F., Sinet, P. M., Delabar, J. M.
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683644/
https://ncbi.nlm.nih.gov/pubmed/1968705
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