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Nucleotide variations in the 3' A gamma enhancer region are linked to beta-gene cluster haplotypes and are unrelated to fetal hemoglobin expression.

Molecular cloning and sequence analysis of a nondeletion form of Sicilian beta o hereditary persistence of fetal hemoglobinemia (HPFH) (mutation in IVS2 nt1 position) homozygous for haplotype III revealed the presence of four sequence variations: C----T at -158 5' to G gamma, T----C at +2285, C...

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Detalhes bibliográficos
Main Authors: Ragusa, A, Lombardo, M, Bouhassira, E, Beldjord, C, Lombardo, T, Nagel, R L, Labie, D, Krishnamoorthy, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683370/
https://ncbi.nlm.nih.gov/pubmed/2472742
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