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Tay-Sachs disease in Moroccan Jews: deletion of a phenylalanine in the alpha-subunit of beta-hexosaminidase.

Tay-Sachs disease is an inherited lysosomal storage disorder caused by defects in the beta-hexosaminidase alpha-subunit gene. The carrier frequency for Tay-Sachs disease is significantly elevated in both the Ashkenazi Jewish and Moroccan Jewish populations but not in other Jewish groups. We have fou...

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書目詳細資料
Main Authors: Navon, R, Proia, R L
格式: Artigo
語言:Inglês
出版: 1991
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683003/
https://ncbi.nlm.nih.gov/pubmed/1825014
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