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Molecular diagnostics for myelin proteolipid protein gene mutations in Pelizaeus-Merzbacher disease.
Pelizaeus-Merzbacher disease (PMD) is a clinically heterogeneous, slowly progressive leukodystrophy. The recent detection of mutations in the myelin proteolipid protein (PLP) gene in several PMD patients offers the opportunity both to design DNA-based tests that would be useful in diagnosing a propo...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
1992
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1682866/ https://ncbi.nlm.nih.gov/pubmed/1376966 |
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