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Allele frequency estimation from data on relatives.

Given genetic marker data on unrelated individuals, maximum-likelihood allele-frequency estimates and their standard errors are easily calculated from sample proportions. When marker phenotypes are observed on relatives, this method cannot be used without either discarding a subset of the data or in...

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Hlavní autor: Boehnke, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682747/
https://ncbi.nlm.nih.gov/pubmed/1985459
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