Use of short sequence repeat DNA polymorphisms after PCR amplification to detect the parental origin of the additional chromosome 21 in Down syndrome.

Lignende værker

• Analysis of DNA polymorphisms suggests that most de novo dup(21q) chromosomes in patients with Down syndrome are isochromosomes and not translocations.
  af: Antonarakis, S E, et al.
  Udgivet: (1990)
• Down syndrome due to de novo Robertsonian translocation t(14q;21q): DNA polymorphism analysis suggests that the origin of the extra 21q is maternal.
  af: Petersen, M B, et al.
  Udgivet: (1991)
• No evidence for a paternal interchromosomal effect from analysis of the origin of nondisjunction in Down syndrome patients with concomitant familial chromosome rearrangements.
  af: Schinzel, A A, et al.
  Udgivet: (1992)
• PCR amplification introduces errors into mononucleotide and dinucleotide repeat sequences
  af: Clarke, L A, et al.
  Udgivet: (2001)
• Parental mosaicism in de novo translocation (21q21q) Down's syndrome.
  af: Croci, G, et al.
  Udgivet: (1991)