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Direct and indirect estimation of the sex ratio of mutation frequencies in hemophilia A.

Carrier detection tests were carried out in 119 families with hemophilia A by using the data obtained with current DNA techniques (e.g., RFLP analysis and direct identification of mutations), conventional carrier detection tests (e.g., factor VIII:C and von Willebrand factor antigen), and pedigree i...

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Detalhes bibliográficos
Main Authors: Oldenburg, J, Schwaab, R, Grimm, T, Zerres, K, Hakenberg, P, Brackmann, H H, Olek, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682491/
https://ncbi.nlm.nih.gov/pubmed/7902674
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