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Normal phenotype with paternal uniparental isodisomy for chromosome 21.

Uniparental disomy (UPD) involving several different chromosomes has been described in several cases of human pathologies. In order to investigate whether UPD for chromosome 21 is associated with abnormal phenotypes, we analyzed DNA polymorphisms in DNA from a family with de novo Robertsonian transl...

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Détails bibliographiques
Auteurs principaux: Blouin, J L, Avramopoulos, D, Pangalos, C, Antonarakis, S E
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682298/
https://ncbi.nlm.nih.gov/pubmed/8213833
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