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Schizophrenia-associated chromosome 11q21 translocation: Identification of flanking markers and development of chromosome 11q fragment hybrids as cloning and mapping resources

Genetic linkage, molecular analysis, and in situ hybridization have identified TYR and D11S388 as markers flanking the chromosome 11 breakpoint in a large pedigree where a balanced translocation, t(1;11)(q43;q21), segregates with schizophrenia and related affective disorders. Somatic cell hybrids, s...

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Detalhes bibliográficos
Main Authors: Fletcher, Judy M., Evans, Kathryn, Baillie, David, Byrd, Philip, Hanratty, Diane, Leach, Suzanne, Julier, Cecile, Gosden, John R., Muir, Walter, Porteous, David J., Clair, David St., van Heyningen, Veronica
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682173/
https://ncbi.nlm.nih.gov/pubmed/8383424
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