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Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21.

In a study of 31 breast cancer families and 12 breast-ovarian cancer families, we have obtained clear evidence of linkage to markers on chromosome 17q in the families with ovarian cancer (maximum lod score 3.34 at theta = .04) but only weak evidence in those without ovarian cancer. Recombinant event...

詳細記述

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書誌詳細
主要な著者: Smith, S A, Easton, D F, Ford, D, Peto, J, Anderson, K, Averill, D, Stratton, M, Ponder, M, Pye, C, Ponder, B A
フォーマット: Artigo
言語:Inglês
出版事項: 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682078/
https://ncbi.nlm.nih.gov/pubmed/8460642
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