THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21.

In order to pinpoint the locale of the gene for early-onset familial breast and ovarian cancer (BRCA1), polymorphisms were developed within the locus for thyroid hormone receptor alpha (THRA1) and for several anonymous sequences at chromosome 17q12-q21. The THRA1 polymorphism is a dinucleotide repea...

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Detalhes bibliográficos
Main Authors: Bowcock, A M, Anderson, L A, Friedman, L S, Black, D M, Osborne-Lawrence, S, Rowell, S E, Hall, J M, Solomon, E, King, M C
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682071/
https://ncbi.nlm.nih.gov/pubmed/8460637
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