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Myotonic dystrophy: size- and sex-dependent dynamics of CTG meiotic instability, and somatic mosaicism.

Myotonic dystrophy (DM) is a progressive neuromuscular disorder which results from elongations of an unstable (CTG)n repeat, located in the 3' untranslated region of the DM gene. A correlation has been demonstrated between the increase in the repeat number of this sequence and the severity of t...

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Main Authors: Lavedan, C, Hofmann-Radvanyi, H, Shelbourne, P, Rabes, J P, Duros, C, Savoy, D, Dehaupas, I, Luce, S, Johnson, K, Junien, C
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682032/
https://ncbi.nlm.nih.gov/pubmed/8098180
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