Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

Although human epidermal growth factor receptor 2 (HER2) overexpression is implicated in tumor progression for a variety of cancer types, how it dysregulates signaling networks governing cell behavioral functions is poorly understood. To address this problem, we use quantitative mass spectrometry to...

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Main Authors: Wolf-Yadlin, Alejandro, Kumar, Neil, Zhang, Yi, Hautaniemi, Sampsa, Zaman, Muhammad, Kim, Hyung-Do, Grantcharova, Viara, Lauffenburger, Douglas A, White, Forest M
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682017/
https://ncbi.nlm.nih.gov/pubmed/17016520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100094
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