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Global analysis of gene function in yeast by quantitative phenotypic profiling

We present a method for the global analysis of the function of genes in budding yeast based on hierarchical clustering of the quantitative sensitivity profiles of the 4756 strains with individual homozygous deletion of nonessential genes to a broad range of cytotoxic or cytostatic agents. This metho...

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Detalhes bibliográficos
Main Authors: Brown, James A, Sherlock, Gavin, Myers, Chad L, Burrows, Nicola M, Deng, Changchun, Wu, H Irene, McCann, Kelly E, Troyanskaya, Olga G, Brown, J Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681475/
https://ncbi.nlm.nih.gov/pubmed/16738548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100043
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