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Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains

Deltex (DTX) and AIP4 are the human orthologues of the Drosophila deltex and Suppressor of deltex, which have been genetically described as being antagonistically involved in the Notch signalling pathway. Both genes encode E3 ubiquitin ligases of the RING (Really interesting new gene)-H2 and HECT (H...

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Autori principali: Chastagner, Patricia, Israël, Alain, Brou, Christel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679774/
https://ncbi.nlm.nih.gov/pubmed/17028573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400822
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