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Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation

Acute lung injury (ALI) causes high mortality, but its molecular mechanisms are poorly understood. Acid aspiration is a frequent cause of ALI, leading to neutrophil sequestration, increased permeability, and deterioration of gas exchange. We investigated the role of platelet-neutrophil interactions...

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Detalhes bibliográficos
Main Authors: Zarbock, Alexander, Singbartl, Kai, Ley, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679711/
https://ncbi.nlm.nih.gov/pubmed/17143330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29499
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