Wnt5a Signaling Induces Proliferation and Survival of Endothelial Cells In Vitro and Expression of MMP-1 and Tie-2

Wnts are lipid-modified secreted glycoproteins that regulate diverse biological processes. We report that Wnt5a, which functions in noncanonical Wnt signaling, has activity on endothelial cells. Wnt5a is endogenously expressed in human primary endothelial cells and is expressed in murine vasculature...

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Hauptverfasser: Masckauchán, T. Néstor H., Agalliu, Dritan, Vorontchikhina, Marina, Ahn, Audrey, Parmalee, Nancy L., Li, Chi-Ming, Khoo, Alan, Tycko, Benjamin, Brown, Anthony M.C., Kitajewski, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679681/
https://ncbi.nlm.nih.gov/pubmed/17035633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-04-0320
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