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Engineering of a novel thioether bridge and role of modified residues in the lantibiotic Pep5.

Pep5 is a 34-amino-acid antimicrobial peptide, produced by Staphylococcus epidermidis 5, that contains the thioether amino acids lanthionine and methyllanthionine, which form three intramolecular ring structures. In addition, two didehydrobutyrines are present in the central part of the lantibiotic...

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Detaylı Bibliyografya
Yayımlandı:Appl Environ Microbiol
Asıl Yazarlar: Bierbaum, G, Szekat, C, Josten, M, Heidrich, C, Kempter, C, Jung, G, Sahl, H G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1996
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167809/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.62.2.385-392.1996
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