Metabolic engineering of Lactococcus lactis: influence of the overproduction of alpha-acetolactate synthase in strains deficient in lactate dehydrogenase as a function of culture conditions.

The als gene for alpha-acetolactate synthase of Lactococcus lactis MG1363 was cloned on a multicopy plasmid under the control of the inducible L. lactis lacA promoter. More than a hundredfold overproduction of alpha-acetolactate synthase was obtained in L. lactis under inducing conditions as compare...

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Veröffentlicht in:	Appl Environ Microbiol
Hauptverfasser:	Platteeuw, C, Hugenholtz, J, Starrenburg, M, van Alen-Boerrigter, I, de Vos, W M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8526510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.61.11.3967-3971.1995
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