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Simultaneous on/off regulation of transgenes located on a mammalian chromosome with Cre-expressing adenovirus and a mutant loxP

The site-specific recombinase Cre has often been used for on/off regulation of expression of transgenes introduced into the mammalian chromosome. However, this method is only applicable to the regulation of a single gene and cannot be used to simultaneously regulate two genes, because site-specific...

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Autors principals: Kondo, Saki, Okuda, Aya, Sato, Hiromi, Tachikawa, Naoto, Terashima, Miho, Kanegae, Yumi, Saito, Izumu
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC167663/
https://ncbi.nlm.nih.gov/pubmed/12853653
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