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mRNA accessible site tagging (MAST): a novel high throughput method for selecting effective antisense oligonucleotides

A solution-based method, mRNA accessible site tagging (MAST), has been developed to map the accessible sites of any given mRNA in high throughput fashion. mRNA molecules were immobilized and hybridized to randomized oligonucleotide libraries. Oligonucleotides specifically hybridized to the mRNA were...

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Autors principals: Zhang, Hong-Yan, Mao, Jianping, Zhou, Daixing, Xu, Yunhe, Thonberg, Håkan, Liang, Zicai, Wahlestedt, Claes
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC167646/
https://ncbi.nlm.nih.gov/pubmed/12853649
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