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Thermodynamic calculations and statistical correlations for oligo-probes design

Optimization of probe design for array-based experiments requires improved predictability of oligonucleotide hybridization behavior. Currently, designing oligonucleotides capable of interacting efficiently and specifically with the relevant target is not a routine procedure. Multiple examples demons...

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Main Authors: Matveeva, O. V., Shabalina, S. A., Nemtsov, V. A., Tsodikov, A. D., Gesteland, R. F., Atkins, J. F.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC167637/
https://ncbi.nlm.nih.gov/pubmed/12853639
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