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Initiation-mediated mRNA decay in yeast affects heat-shock mRNAs, and works through decapping and 5′-to-3′ hydrolysis

The degradation of mRNA in the yeast Saccharomyces cerevisiae takes place through several related pathways. In the most general mRNA-decay pathway, that of poly(A)-dependent decay, the normal shortening of the poly(A) tail on an mRNA molecule by deadenylation triggers mRNA decapping by the enzyme Dc...

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Publicat a:Nucleic Acids Res
Autors principals: Heikkinen, Heather L., Llewellyn, Sara A., Barnes, Christine A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167635/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg474
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