Initiation-mediated mRNA decay in yeast affects heat-shock mRNAs, and works through decapping and 5′-to-3′ hydrolysis

The degradation of mRNA in the yeast Saccharomyces cerevisiae takes place through several related pathways. In the most general mRNA-decay pathway, that of poly(A)-dependent decay, the normal shortening of the poly(A) tail on an mRNA molecule by deadenylation triggers mRNA decapping by the enzyme Dc...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Heikkinen, Heather L., Llewellyn, Sara A., Barnes, Christine A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167635/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853617/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg474
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