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RNA- and Virus-Independent Inhibition of Antiviral Signaling by RNA Helicase LGP2

Antiviral innate immune responses can be triggered by accumulation of intracellular nucleic acids resulting from virus infections. Double-stranded RNA (dsRNA) can be detected by the cytoplasmic RNA helicase proteins RIG-I and MDA5, two proteins that share sequence similarities within a caspase recru...

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Main Authors: Komuro, Akihiko, Horvath, Curt M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1676302/
https://ncbi.nlm.nih.gov/pubmed/17020950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01325-06
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