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Rotavirus Nonstructural Glycoprotein NSP4 Is Secreted from the Apical Surfaces of Polarized Epithelial Cells

NSP4, a nonstructural glycoprotein encoded by rotavirus, is involved in the morphogenesis of virus particles in the endoplasmic reticulum of infected cells. NSP4 is also implicated in the pathophysiology of rotavirus-induced diarrhea by acting as an enterotoxin. To mediate enterotoxic effects in viv...

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Autors principals: Bugarc̀ić, Andrea, Taylor, John A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1676281/
https://ncbi.nlm.nih.gov/pubmed/17035333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01378-06
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