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Development and testing of improved suicide functions for biological containment of bacteria.

We have developed very efficient suicide functions for biological containment based on the lethal Escherichia coli relF gene. The suicide functions are placed in duplicate within a plasmid and arranged to prevent inactivation by deletion, recombination, and insertional inactivation. The efficiency o...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Appl Environ Microbiol
Hauptverfasser: Knudsen, S, Saadbye, P, Hansen, L H, Collier, A, Jacobsen, B L, Schlundt, J, Karlström, O H
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7793926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.61.3.985-991.1995
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