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Development and testing of improved suicide functions for biological containment of bacteria.

We have developed very efficient suicide functions for biological containment based on the lethal Escherichia coli relF gene. The suicide functions are placed in duplicate within a plasmid and arranged to prevent inactivation by deletion, recombination, and insertional inactivation. The efficiency o...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Principais autores: Knudsen, S, Saadbye, P, Hansen, L H, Collier, A, Jacobsen, B L, Schlundt, J, Karlström, O H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7793926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.61.3.985-991.1995
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