Cloning and molecular analysis of the dihydrofolate reductase gene from Lactococcus lactis.

The Lactococcus lactis gene encoding trimethoprim resistance has been cloned and expressed in Escherichia coli and Bacillus subtilis. Several lines of evidence indicate that the cloned gene encodes dihydrofolate reductase (DHFR). (i) It fully complements the fol "null" mutation in E. coli. (ii) Nucl...

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Leszczyńska, K, Bolhuis, A, Leenhouts, K, Venema, G, Cegłowski, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7574597/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.61.2.561-566.1995
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