Identification of the E9^E2C cDNA and Functional Characterization of the Gene Product Reveal a New Repressor of Transcription and Replication in Cottontail Rabbit Papillomavirus

Cottontail rabbit papillomavirus (CRPV) genomes mutated in the trans-activation domain of the E2 protein, which stimulates both viral DNA replication and transcription, are severely impaired in their ability to induce tumors in New Zealand White rabbits. A number of papillomaviruses encode, in addit...

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Bibliographic Details
Main Authors: Jeckel, Sonja, Loetzsch, Ekaterina, Huber, Evamaria, Stubenrauch, Frank, Iftner, Thomas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC167252/
https://ncbi.nlm.nih.gov/pubmed/12885893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8736-8744.2003
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