Local Delivery of CpG Oligodeoxynucleotides Induces Rapid Changes in the Genital Mucosa and Inhibits Replication, but Not Entry, of Herpes Simplex Virus Type 2

Mucosal surfaces are the entry sites for the vast majority of infectious pathogens and provide the first line of defense against infection. In addition to the epithelial barrier, the innate immune system plays a key role in recognizing and rapidly responding to invading pathogens via innate receptor...

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Pubblicato in:	J Virol
Autori principali:	Ashkar, Ali A., Bauer, Stefan, Mitchell, William J., Vieira, Jeff, Rosenthal, Kenneth L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Vaccines and Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12885911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.16.8948-8956.2003
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