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Local Delivery of CpG Oligodeoxynucleotides Induces Rapid Changes in the Genital Mucosa and Inhibits Replication, but Not Entry, of Herpes Simplex Virus Type 2

Mucosal surfaces are the entry sites for the vast majority of infectious pathogens and provide the first line of defense against infection. In addition to the epithelial barrier, the innate immune system plays a key role in recognizing and rapidly responding to invading pathogens via innate receptor...

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Autors principals: Ashkar, Ali A., Bauer, Stefan, Mitchell, William J., Vieira, Jeff, Rosenthal, Kenneth L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC167233/
https://ncbi.nlm.nih.gov/pubmed/12885911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8948-8956.2003
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